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& De Las Peas, A

[Epub ahead of print] Ishikawa H et al

genetic issues with detoxification enzyme production

Previous studies have demonstrated that heme accumulates in lipid droplets within the digestive vacuoles of malaria parasites [32,33,34,35,36,37,38]

The source of the mitochondrial superoxide production is likely the respiratory chain, since APAP has been shown to inhibit respiration through complex II by 47% in isolated mouse hepatocytes, while complex I activity was affected to a lesser extent37,38