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However, the mechanism of metabolic dysregulation in affecting the progress and disease severity of SCD has not been well characterized, especially when exposed to excess hemin

In the critical redox system of mammalian cells, glutathione peroxidase (GPX) is the most prominent family of proteins with a multifaceted function that affects almost all cellular processes

Modulating eryptosis, whether by inducing or inhibiting the process, could help regulate erythrocyte survival to prevent premature cell loss or promote the removal of damaged erythrocytes, thereby contributing to the proper balance of blood cell counts

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Separation was conducted at a constant temperature of 30 C using a mobile phase of 5% (v/v) acetonitrile, 0.05% (v/v) trifluoroacetic acid, and 0.1 M sodium perchlorate at a flow rate of 0.5 mL/min