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Free Radic Biol Med 46 , 16331638, (2009)

The first signs may be subtle: a progressive and insidious decline in cognitive faculties, accompanied by a daily sensation of mental fog

However, not all samples were consistent with the declarations

Different proteins are degraded at different rates, ranging from a few minutes for metabolic enzymes, weeks for actin and myosin, to months for hemoglobin[2]