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PMID 15135771

Over that timeline, the input can be referenced in multiple systems and multiple document types

Nature 496 , 469476 (2013)

Kaufmann nothing to disclose, Anna Boronylo: nothing to disclose

Further mechanistic studies showed that NNMTi increases intracellular NAD levels and activates the SIRT1 pathway by inhibiting NNMT, thereby suppressing the transcription of adipogenic genes and preventing the maturation of preadipocytes.This research provides a new perspective for understanding the molecular mechanism of adipocyte differentiation, confirms the key role of NNMTi in regulating adipogenesis, and lays a foundation for subsequent obesity intervention studies