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doi: 10.3389/fimmu.2019.01266 166 SrikrishnaGNayakJWeigleBTemmeAFoellDHazelwoodLet al

Aging 20 , 503512 (1999)

Non-canonical activation of the DNA sensing adaptor STING by ATM and IFI16 mediates NF-B signaling after nuclear DNA damage

While direct reproductive toxicity has been extensively documented, the mechanisms underlying heritable reproductive dysfunction represent an emerging frontier requiring intensive investigation ( Figure 3 )