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Together, these effects lead to the immunogenic cell death of tumor cells and alleviate PD-L1-mediated immune evasion, which further remodels the immunosuppressive TME and triggers a robust immune response, effectively inhibiting bilateral tumor progression and metastasis [76]

If the insert is intended for insertion into the vagina, it is called a vaginal insert, vaginal suppository, or pessary (2)

Possible structures are illustrated below

and (3) increased metabolite abundance such as glutathione disulfide and lactate (4, 21, 32, 34) ( Figure 7A & 7D )

Furthermore, the model output strongly correlates with quantitative GSH reactivity data in chemically diverse, external datasets