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What is nicotine and other facts PMI Philip Morris International Most tobacco products, including e cigarettes, contain nicotine, a chemical that can harm the heart, brain and whole body. As with other addictive products, using a nicotine product builds tolerance, leading to more Cigarettes and Other Types of Tobacco Products Nicotine is highly addictive and affects both the brain and body. Whether it's vaping or smoking, nicotine can lead to dependence, cravings, and serious health risks over time. Understanding how nicotine works Tobacco carcinogens, their biomarkers and tobacco induced cancer Nature Reviews Cancer

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