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Description

Briefly, plates were washed with 1 PBS and blocked with RPMI (ThermoFisher 72400-047) containing 10% FBS (ThermoFisher A38400-01) for 1 h at 37 C

Future investigation using verified formulations and prospective clinical study designs is necessary to determine whether peptide-based therapies can be safely and meaningfully integrated into orthopedic care.

Clogged Pores

Pull down enrichment quantification was performed using normal qPCR with reverse transcription as above described with the primer set in Supplementary Table 2

The twice-weekly cadence is pharmacologically coherent given a 5.88.1 day half-life: dosing every 34 days means the second dose lands while roughly half the first is still conjugated to albumin, producing the smoothed steady-state the molecule was designed for