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Dual targeting macrophages and microglia is a therapeutic vulnerability in models of PTEN-deficient glioblastoma

It is also possible to lyophilize the compounds of Formula I and their pharmaceutically acceptable salts and to use the resulting lyophilisates, for example, for preparing preparations for injection or infusion

Mitochondrial therapeutics have been found to address key steps in each of these underlying pathologies, and many therapies overlap in areas of influence and action