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Agarwal R, Filippatos G, Pitt B, et al

doi:10.1016/0049-3848(92)90030-e Fakhar H, Hashemi Tayer A

Patients considering IGF-1 LR3 should undergo comprehensive evaluation to determine whether peptide therapy is appropriate and whether safer alternatives may achieve similar goals

Loss of SIRT4 decreases GLT-1-dependent glutamate uptake and increases sensitivity to kainic acid

They provide a clear link between biochemical disruptions, such as dopamine depletion and neuroinflammation, and the resulting cognitive, psychiatric, and motor symptoms observed in chronic METH abusers