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Milk thistle extract (100mg, standardised to 80mg silymarin flavonoids) is a botanical ingredient with a long history of use as a dietary supplement

Lagas JS, Fan L, Wagenaar E et al (2010) P-glycoprotein (P-gp/Abcb1), Abcc2, and Abcc3 determine the pharmacokinetics of etoposide

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