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A pre-specified criterion was established to terminate the trial if the sample size re-estimation indicated that more than 250 participants would need to be randomised in order to detect the expected effect

Supplementary file Table 2 evaluates within the former-smoker subsample whether pre-cessation tobacco dependence is associated with two chronic disease outcomes

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Using a stress ball is simple: hold it in one hand and squeeze it repeatedly, focusing on the sensation of the ball in your hand and the muscles contracting and relaxing

But even by 1946, the concept was still novel enough that a manual called Self-Service Food Stores found it necessary to advise that "food retailers must adopt some, if not all, of the features of self-service store operation if they are to prosper", such as the fact that goods displayed at eye level are easier for customers to see