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Bacteriostatic Water is manufactured to Water for Injection USP standards, requiring production by distillation or reverse osmosis from a suitable water source, testing for bacterial endotoxins below 0.25 EU/mL by the LAL method, sterility testing by membrane filtration to confirmed absence of microbial contamination, particulate matter testing below USP limits, pH within the 4.57.0 range, and osmolality confirmation consistent with a non-electrolyte aqueous solution

2024;21(2):e14748

These results demonstrate that SPAE effectively reduces DEX-induced DNA damage in hepatic tissues, with the 800 mg/kg dose offering greater genoprotective effects than 400 mg/kg (Table 4

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This baseline allows objective comparison at three, six, and twelve months