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In the case of HIV-1, neutralizing antibodies prevent the virus from entering target cells expressing the CD4 receptor and the co-receptor CC-chemokine receptor 5 (CCR5) or CXC-chemokine receptor 4 (CXCR4)

43 A number of other animal model studies have also demonstrated that genetic deficiency in negative regulators of the canonical NF-B pathway, such as the deubiquitinases CYLD and A20, promotes colonic inflammation

The American Heart Association includes CRAO in its definition of an acute ischemic stroke, a sudden episode of neurological dysfunction caused by a lack of blood flow to the brain, spinal cord, or retina

56 Two longer-term studies, 48 and 52 weeks, respectively, found significant improvements in NAFLD/NASH activity score with NAC, 1200 mg per day, together with metformin

Different host-tissue microenvironments select for cancer cells with distinct metastatic traits, which gives rise to organ-specific populations of metastatic cells [14]