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If you're pregnant, your needs go up to 2.6 micrograms a day, while you'll need 2.8 micrograms a day if you're breastfeeding, the organization says

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Lin C, Ma R, Zeng X, Zhang B, Cao T, Jiao S, Chen H, He Y, Liu M, Cai H (2024) Integration of genomics, clinical characteristics and baseline biological profiles to predict the risk of liver injury induced by high-dose methotrexate