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For example, interleukin 13 (IL-13) selectively induce claudin 2 expression to enhance pore pathway permeability [16]

Carmichael ST, Kathirvelu B, Schweppe C, Nie EH

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Glucose & insulin: GH can cause insulin resistance and raise blood glucose

For example, in a 16-week, placebo-controlled trial of an age-advanced cohort receiving nightly subcutaneous GHRH analogue (a sermorelin-like peptide), treatment activated endogenous GH pulsatility and significantly increased integrated nocturnal GH levels