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Its potential against acute and latent M.tb infections is still under investigation, and small-scale clinical trials may be necessary to assess its anti-TB efficacy either as a monotherapy or in combination with other anti-TB drugs

Braunschweig: in Verlegung Christof Friederich Zilligern, 1651

MRPL13 knockdown can upregulate the expression of pro-apoptotic genes (BAX and cleaved caspase-3) and downregulate the expression of anti-apoptotic genes (BCL-2) to significantly increase apoptosis

Los niveles de GSH disminuidos juegan un importante rol en la iniciacin del proceso de apoptosis y la disminucin drstica de los niveles de GSH especialmente a nivel mitocondrial, llevan a la disfuncin mitocondrial y sobreviene la muerte celular (19)