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Proc Natl Acad Sci USA 93: 42134218 [DOI] [PMC free article] [PubMed] [Google Scholar] Fischer O.M., Giordano S., Comoglio P.M., Ullrich A

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468 In a transgenic mouse model of DN-NAMPT, the researchers found that middle-aged mice had a systemic reduction of NAD + and showed a moderate NAFLD phenotype, like triggered inflammation, lipid accumulation, increased oxidative stress and impaired insulin sensitivity of liver