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Citation: Mileo AM, Abbruzzese C, Mattarocci S, Bellacchio E, Pisano P, Federico A, et al

The activation of AngII/AT1R/Nox axis via the generation of ROS, has been found to be associated with mitochondrial injury

Homocysteine levels are positively correlated with age, which may be caused by deficiencies in folate, vitamin B6, and vitamin B12, kidney impairment, and reduced activity of the enzymes involved in the elimination of Homocysteine (Al Mutairi 2020