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I also have slight chest pressure, I have had this before after a long time without B12 and then having too much at once

Best Times To Take Glutathione Before meals: Improve absorption by taking glutathione on an empty stomach at least 30 minutes before eating

Most practitioners recommend starting at 250-300 mcg daily to assess tolerance, then potentially increasing to 400-500 mcg if initial response is suboptimal and no side effects occur

Years ago, I started taking a vitamin B12 supplement