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The datasets had already been robust multi-array average-normalized in batches using the makecdfenv, affy and limma R packages, and batch-corrected using the ComBat method in the sva R package

Under conditions of oxidative stress, Grx participates in the S-glutathionylation process, while when oxidative stress is reduced, it catalyzes the deglutathionylation reaction (Lu, 2013

This approach could potentially be adapted for broader biomarker selection or drug target identification efforts, where efficient processing of large-scale biological data and literature is crucial

10.1006/jmbi.1998.1900 [DOI] [PubMed] [Google Scholar] Brown N

J Food Compos Anal 19(67):669675