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SKU: 89045096876
Price: 22.59 USD
Availability: InStock
Rating: 4.5085 (27 reviews)

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SKU: 89045096876 · From hgidocs.co

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Description

A study indicated that sorafenib led to the degradation of mitofusin-2 (MFN2) in lysosomes by promoting PINK1-Parkin-mediated mitophagy in cardiomyocytes, and the decrease in MFN2 increased the expression of calmodulin-dependent protein kinase II delta (CaMKII), thereby contributing to cardiac necroptosis [100]