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Relationship between frequency of MTHFR polymorphisms and latitude Frequency of the MTHFR -C677T T allele in the Eurasia region is shown in Figure 2

Reprogramming science The discovery of the reprogramming recipe earned a Nobel Prize for Japanese biologist Shinya Yamanaka in 2012

(2019) 51:e13279

High level PHGDH expression in breast is predominantly associated with keratin 5-positive cell lineage independently of malignancy

Hi-C analysis revealed 1,163 caQTLs overlapping chromatin loop anchors, with 116 showing coordinated regulation where variants exhibit both chromatin accessibility and gene expression/splicing effects within the same chromatin loop (e.g., rs4820586-A increasing ADORA2A accessibility and both expression and splicing)