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Members of the TNF superfamily and angiotensin II (Ang II) are prominent activators of NF-B in renal pathologies ( 2.2.3 Apoptosis and renal disease Apoptosis, evident through podocyte depletion and tubular cell attrition, exacerbates the decline in renal epithelial cells, a hallmark of both AKI and CKD ( Consistent with this finding, autophagosomes were detected in murine renal tubular cells following I/R injury

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