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Kromdijk et al., 2016

Abstract Liver diseases, including hepatocellular carcinoma (HCC), non-alcoholic fatty liver disease (NAFLD), and alcoholic liver disease (ALD), impose a significant global health burden, with over 2 million deaths annually and substantial economic losses

Once a drug products range of allowable denaturation has been identified, the next step in this process requires full denaturation of the protein solution as confirmed via physical separations of aggregates or characterization of tertiary or secondary structural changes

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Response of recalcitrant generalized morphea to intravenous immunoglobulins (IVIg): three cases and a review of the literature