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Over the past decade or so, numerous diseases have been linked to ferroptosis as part of their etiology, including cancers, metabolic disorders, autoimmune diseases, central nervous system diseases, cardiovascular diseases, and musculoskeletal diseases

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However, when analyzing the effect of 2DG treatment on clonogenic survival upon irradiation, we observed that 2DG did almost not alter clonogenic survival of TrC1 AKT-WT cells whereas radiosensitivity of TrC1 AKT-E17K cells was slightly decreased, at least at a higher single irradiation dose (8 Gy) ( Figure 3L )

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