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10.1016/j.cmet.2019.11.019 147 PoltorakA.HeX.SmirnovaI.LiuM

"FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice"

If a simple tripeptide could shift old tissue behavior toward a younger pattern, it suggested a broader role in tissue maintenance and repair that might operate across multiple organ systems