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Indeed, marine mammals possess high GSH levels both in tissues and in circulation, and diving mammals display positive selection for, and duplications of, genes along the GSH metabolic pathway

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Key effects include: Delivers bioavailable copper to activate critical copper-dependent enzymes Stimulates collagen, elastin, and glycosaminoglycan production, helping skin, tendons, and connective tissues regenerate Accelerates wound healing and supports remodeling of old or fibrotic tissue Regulates matrix metalloproteinases (MMPs) to balance tissue breakdown and rebuilding Reduces inflammation by lowering cytokines such as TNF-, IL-6, and TGF- Provides antioxidant protection by boosting copper-dependent enzymes Supports hair follicle health and dermal papilla cell activity Influences gene expression related to repair, regeneration, and cell protection Improves tissue resilience in skin, muscle, and joint structures May support cognitive and neural protection through antioxidant and anti-inflammatory mechanisms Key Research Areas and Potential Benefits 1

[DOI] [PubMed] [Google Scholar] [143].Patel S, Wainer IW, Lough WJ, Affinity-based chiral stationary phases, in: Hage DS (Ed.), Handbook of Affinity Chromatography, 2nd ed., CRC Press, Boca Raton, 2006: pp