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Often called the "universal antioxidant," ALA is unique because it is both water-soluble and fat-soluble

Additionally, it activates PP2A to reduce Tau protein hyperphosphorylation (189) and inhibits the nucleotide-binding oligomerization domain-, leucine-rich repeat- and pyrin domain-containing protein 3/NF-B signaling pathway to alleviate neuroinflammation (190) (Figure 6C)