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The data demonstrate the inhibitory effect of Epitalon in the development of spontaneous mammary tumors in HER2/neu mice, suggesting that a downregulation of HER2/neu gene expression in mammary adenocarcinoma may be responsible, at least in part, for the antitumor effect of the peptide

In summary, it can be concluded that the inoculation with BacA strain induces the upregulation of proinflammatory cytokines earlier as it is less virulent and more vulnerable compared to wild-type MAP

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It is primarily produced in the pancreas in response to ingestion of food and in proportion to caloric load (191)

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