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Glutathione Reductase (GR) The relationship between hydrogen water and glutathione reductase represents a fascinating interplay between exogenous antioxidant support and endogenous enzymatic systems

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For instance GPx-1, which is the most abundant one in this family, is found mostly in the cytosol and in the matrix part of the mitochondria 11,13 , GPx-2 and GPx-3 are respectively observed in some types of endothelial cells and in the extracellular matrix 11,14 , GPx-4 mostly protects the biomembrane and the liposomes 11,15,16 and, has mitochondrial, cytosolic and nucleic forms and finally GPx-5 and GPx-6 are respectively expressed in the epididymis and the olfactory epithelium 11