glutathione protein modification Redox Regulation by S-Glutathionylation: From Molecular Mechanisms to Implications in Health and Disease Frontiers | Plant Glutathione Biosynthesis:

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Both microarray and serial analysis of gene expression techniques have been used to examine expression profiles in sporocysts, with a variety of proteases (cathepsin C, preprocathepsin L, hemoglobinase, and elastase) and antioxidants (Cu/Zn superoxide dismutase, peroxiredoxins 1 and 2, and glutathione peroxidase) having been identified as upregulated factors potentially responsible for some of the inhibitory effects seen in the host (50, 51)

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For example, coronary artery disease (CAD) is caused by cholesterol deposits and inflammation that damage the coronary arteries, leading to atherosclerosis which results in insufficient oxygen and blood supply