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Low GH status in obesity is mainly considered a functional condition, largely reversible after sustained weight loss [18]

Additional investigations include brain magnetic resonance imaging, and the identification of ATP7B mutations [17] based on which the prevalence rate of WD is now estimated to be 1 in 7,026 people compared to 1 in 35,000-45,000 people before the advent of this molecular investigation [18]

This dual role, stimulating both synthesis and controlled degradation, is characteristic of wound healing rather than simple collagen accumulation

Turner's syndrome accounted for the second-largest market share in 2025 and is expected to emerge as a profitable category during the projected period