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M.GriffinE

In: Berovic, M., Zhong, JJ

Sci Rep 5:8694

When ROS production exceeds scavenging capacity, oxidative stress ensuesa core driver of atherosclerosis [320]

CNs APPEAR IN LATE CHILDHOOD AND CONTINUE TO DEVELOP THROUGHOUT LIFE CNs typically begin to arise in late childhood or early adolescence and continue to accumulate throughout the lifetime, affecting 99% of adults with NF1 [31,32]