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In all models, other determinants of depressive symptoms included sex, education, chronic disease, BMI, antidepressant use at baseline, subthreshold depressive symptoms and vitamin D status as reported previously (Reference Briggs, McCarroll and OHalloran20)

When growth hormone binds to receptors in muscle, bone, cartilage, and organ tissues, it stimulates protein synthesis, cell proliferation, tissue hypertrophy, and structural growth