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Similarly, peroxisome proliferator-activated receptor (PPAR)- agonists such as fenofibrate promote fatty acid oxidation, which may help clear the lipid accumulation associated with mitochondrial dysfunction and reduce inflammation-driven atherosclerosis (159)

It was shown that the deletion of E155 in GSTO1-1 has a significant effect on enzymatic stability and may consequently alter the physiologic role of the enzyme in the brain regions 53

PubMed, Engevik, Melinda A., et al

In addition, the promoting role of P300/CBP and its associated factors in the aging process of microglia in Alzheimers disease (AD) has also been observed