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Insulin sensitivity was assessed by total GDR measured during the hyperinsulinemiceuglycemic clamp in a subgroup of 50 patients [27] and by homeostatic model assessment in all patients [28]

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10.1038/s41398-018-0353-x 72

20 It is known that NOS increases in cerebral ischemia 21 and the overexpression of this enzyme causes relevant tissue damage: the overall result is a detrimental action on the cell membrane

Future studies with larger and more diverse participant pools would help to capture the variability in individual responses better and provide more robust data