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Richardson BG, Jain AD, Speltz TE, Moore TW

Cevimeline activates receptors more selectively, but has similar side effects

Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses

This suggests that the cells rely on GPX4 to resist oxidative stress, and this could potentially increase their sensitivity to RSL3, a ferroptosis inducer that targets GPX4

The findings of some of the clinical trials in which lipoic acid administration has been tested in diabetic patients during the last 10 years are summarized