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The structure of MSA-DH was determined by molecular replacement using a model generated by Alpha-Fold2 (Jumper et al., 2021) as a search-model for Phaser (McCoy et al., 2007) from the Phenix suite (Adams et al., 2010)

An expanded genetic code with a functional quadruplet codon

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Spinal GSH levels and oxidized proteins are similar in injured xCT+/+ and xCT/ As System xc acts as an importer of cystine across the membrane and is as such involved in the replenishment of intracellular glutathione, we sought to know to what extent the deletion of the xCT subunit would alter GSH production