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Description

Zhu et al., 2020)

Methylmalonic acid In the conversion of methylmalonyl CoA to succinyl CoA, where adenosylcobalamin plays a fundamental role as a cofactor, there is a defect in this reaction if there is not enough vitamin B12

In most cases, OH manifests with non-specific symptoms and complaints, such as orthostatic dizziness, light-headedness or blurred vision, but it may cause orthostatic syncope, increasing risk of injurious falls and their complications, often leading to hospitalization