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Circadian regulation of physiological processes: reciprocal signaling between the clock and other regulatory networks In addition to their primary role as generator of circadian rhythm, the biological clock serves a key role in controlling physiological functions of almost all tissues and organs in two major ways

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Genetic engineering was successfully used to increase folate production by Lactococcus lactis and to transform a folate consumer, Lactobacillus gasseri , into a folate producer 867,868,869,870,871,872