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Hence, we investigated ferroptosis sensitivity of hepatocytes exposed to MASH environment (high glucose, insulin, tumor necrosis factor-, interleukin-1 and transforming growth factor-) with different species of fatty acids, i.e., oleic acid (OA 18:1, MUFA) and palmitic acid (PA 16:0, SFA), arachidonic acid (AA 20:4, -6 PUFA) or docosahexaenoic acid (DHA 22:6, -3 PUFA)

Several in vitro studies showed that various mushrooms have antihypertensive constituents, particularly peptides and triterpenes which have the potential to protect from high blood pressure and eventually minimize the risk of hypertension by suppressing the activity of the ACE and renin angiotensin-aldosterone system

Campanale A, Inserra A, Comai S