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In AD patients, the concentration of free copper (i.e., copper not bound to ceruloplasmin) is elevated, and free copper can cross the blood-brain barrier (BBB) to enter the cerebrospinal fluid (CSF) and cerebral cortex, where it interacts with A to promote its aggregation (83)

Despite this limitation, we tried to estimate the composition of HSPCs based on targeted DNAm analysis with pyrosequencing

In 3D tumor models, De Vitis et al

Topical Application: For skin injuries, topical preparations have been used in research, typically applied 2 to 3 times per day directly to the affected area

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