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Effect of proteolytic enzymes on the binding of cobalamin to r protein and intrinsic factor: in vitro evidence that a failure to partially degrader protein is responsible for cobalamin malabsorption in pancreatic insufficiency [Efecto de las enzimas proteolticas sobre la unin de la cobalamina a la protena R y al factor intrnseco: evidencia in vitro de que la falta de protenas parcialmente desgradadas es responsable de la mala absorcin de la cobolamina en la insuficiencia pancretica]

In premarketing clinical trials, 2 patients are known to have developed a serious cutaneous systemic illness