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The first step is the transformation of D-glucose to D-glucose-6-phosphate, followed by its transformation into D-fructose-6-phosphate by phosphomannose isomerase (PMI)

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Its also about ensuring your body and your immune system can repair and recover

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Cell Death Differ 14(7):12671274 Gupte SS, Hackenbrock CR (1988) J Biol Chem 263:52485253 Hackenbrock CR, Chazotte B, Gupte SS (1986) J Bioenerg Biomemb 18:331368 Hancock JT, Desikan R, Neill SJ (2001) Does the redox status of cytochrome C act as a fail-safe mechanism in the regulation of programmed cell death

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Heat stress activates thermoregulatory mechanisms (increased cardiac output, sweating), but uncompensated fluid/electrolyte loss induces mild illnesses (heat syncope, cramps, exhaustion) or severe heat stroke (HS) [3, 4]

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