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During heat stress, altering diet composition has been shown to stimulate feed intake, partially compensating for reduced consumption (Renaudeau et al., 2012)

In the future, in-depth analysis of the ASCT2 3D structure using structural biology techniques and an in-depth understanding of the interaction mechanism between ASCT2 and inhibitors will help to optimize the structure of inhibitors and improve their efficacy

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Although the exact mechanisms by which ketogenic diets exert their effects are not fully known, it is believed that these effects are partially mediated through interactions with the gut microbiome [109,110,111]